Study of PARG inhibitor FORX-428 for advanced solid tumors
Part of Cancer clinical trials.
This trial tests a new drug called FORX-428, which targets a protein called PARG, in people with advanced solid tumors. It is for patients whose cancer has not responded to prior treatments and who have specific genetic changes, such as BRCA mutations.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have an advanced or metastatic solid tumor that has progressed after at least one prior treatment.
- Your tumor must have certain genetic changes, like BRCA1/2 mutations or other signs of DNA repair problems (your doctor can check this).
- You must have measurable disease (tumors that can be seen on scans).
- You must have adequate organ function, which will be checked with blood tests.
- You must be able to swallow pills and have no gut problems that affect absorption.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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