Clin2
NCT07362459Possibly a fitRecruiting

Study of SCTB14 for untreated advanced non-small cell lung cancer

Non-Small Cell Lung Carcinoma (NSCLC)

Treatments studied

Part of Cancer, Lungs & breathing clinical trials.

This trial tests a new drug, SCTB14, as a first treatment for advanced non-small cell lung cancer that has a high level of PD-L1. It aims to see if the drug is safe and effective for people who haven't had other treatments for their cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
246 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must have stage IIIB, IIIC, or IV non-small cell lung cancer that can't be removed with surgery or cured with chemo and radiation.
  • Your tumor must have a PD-L1 score of at least 10% (a test that looks for a protein on your cancer cells).
  • You should not have had any prior chemotherapy, immunotherapy, or targeted therapy for this lung cancer.
  • You need to be in generally good health (able to care for yourself and up and about at least half the day).
  • You cannot have certain gene mutations in your tumor (such as EGFR, ALK, ROS1, or others).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06505824Recruiting· Phase 1
Study of BL-M14D1 for advanced lung cancer and other solid tumors

This trial tests a new drug, BL-M14D1, for people with advanced small cell lung cancer, neuroendocrine tumors, or other solid tumors that have no standard treatment. The goal is to see if the drug is safe and possibly effective.

Shanghai, Shanghai Municipality
NCT06304818Not yet recruiting· Phase 1/Phase 2
Test of a new drug for advanced solid tumors

This trial tests a new drug called SCTB14 for people with advanced solid tumors. The goal is to see if it is safe and whether it helps shrink or slow the cancer.

NCT07662395Recruiting· Phase 2/Phase 3
New drug plus chemo for advanced squamous lung cancer

This trial tests a new drug (SCTB41) combined with chemotherapy for people with advanced squamous non-small cell lung cancer who have not had any prior treatment. It aims to see if this combination works better than standard therapy.

Guangzhou, Guangdong
NCT07609251Not yet recruiting· Phase 2
Combination therapy for advanced non-small cell lung cancer

This study tests a new combination treatment (SCTB41 plus docetaxel) for people with advanced non-small cell lung cancer who have already tried other treatments. The goal is to see if this combination can help shrink or control the cancer.

Wuhan, Hubei
NCT06600022Recruiting· Phase 1/Phase 2
Studying SCTB41 for advanced solid tumors

This trial tests a new drug called SCTB41 in people with advanced solid tumors that have not responded to other treatments. The goal is to see if it is safe and if it shrinks tumors.

Guangzhou, Guangdong
NCT05142189Recruiting· Phase 1
Testing BNT116 for advanced non-small cell lung cancer

This trial tests an experimental immunotherapy called BNT116, given alone or with other drugs, for people with advanced non-small cell lung cancer (NSCLC). The goal is to see if it is safe and if it can help shrink tumors.

Lexington, Kentucky

Hear when a new Non-Small Cell Lung Carcinoma (NSCLC) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.