Clin2
NCT07609251Possibly a fitNot yet recruiting

SCTB41 Plus Docetaxel for Advanced Lung Cancer

NSCLC (Advanced Non-small Cell Lung Cancer)

Treatments studied

Part of Cancer, Lungs & breathing clinical trials.

This trial tests a combination of two drugs—SCTB41 (a new immunotherapy) and docetaxel (a chemotherapy)—in patients with advanced non-small cell lung cancer who have already tried other treatments. The goal is to see if this combination can slow or stop cancer growth.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
90 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have advanced lung cancer (Stage IIIB, IIIC, or IV) that cannot be surgically removed or treated with radiation and chemotherapy together
  • Your cancer has grown or returned after treatment with immunotherapy (PD-1/PD-L1 inhibitors) and/or chemotherapy
  • You have not previously received the drug docetaxel
  • You have good overall health and can perform light activity (ECOG score 0–1)
  • You have at least one tumor that can be measured on imaging and is not in the brain
  • Your major organs (liver, kidneys, heart, lungs) are working well enough for treatment

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07662395Recruiting· Phase 2/Phase 3
New drug plus chemo for advanced squamous lung cancer

This trial tests a new drug (SCTB41) combined with chemotherapy for people with advanced squamous non-small cell lung cancer who have not had any prior treatment. It aims to see if this combination works better than standard therapy.

Guangzhou, Guangdong
NCT07362459Recruiting· Phase 3
Study of SCTB14 for untreated advanced non-small cell lung cancer

This trial tests a new drug, SCTB14, as a first treatment for advanced non-small cell lung cancer that has a high level of PD-L1. It aims to see if the drug is safe and effective for people who haven't had other treatments for their cancer.

Shanghai, Shanghai Municipality
NCT07144280Recruiting· Phase 3
Study of a new drug vs docetaxel for advanced lung cancer

This trial tests a new experimental drug called PF-08046054/SGN-PDL1V against a standard chemotherapy (docetaxel) for people with a type of advanced lung cancer that has PD-L1 protein on at least 1% of tumor cells and has progressed after prior treatments. The goal is to see if the new drug works better or has fewer side effects.

Alabaster, Alabama
NCT05922345Recruiting· Phase 3
Study drug vs docetaxel for advanced lung cancer after prior treatment

This Phase 3 trial compares AL2846 pills plus TQB2450 injections against standard chemotherapy (docetaxel) in people with advanced non-small cell lung cancer. You may qualify if your cancer has progressed after platinum chemotherapy and immunotherapy, and if certain tumor genetic tests are negative.

Hefei, Anhui
NCT06600022Recruiting· Phase 1/Phase 2
Studying SCTB41 for advanced solid tumors

This trial tests a new drug called SCTB41 in people with advanced solid tumors that have not responded to other treatments. The goal is to see if it is safe and if it shrinks tumors.

Guangzhou, Guangdong
NCT07633873Not yet recruiting· Phase 3
New Drug Combination for Advanced Lung Cancer Treatment

This trial tests whether a new drug combination (SYS6010 plus enlonstobart) works better than standard immunotherapy with chemotherapy for patients with advanced non-small cell lung cancer. You may qualify if you have not received prior cancer treatment and have a specific marker (PD-L1) on your tumor.

Hear when a new NSCLC (Advanced Non-small Cell Lung Cancer) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.