Clin2
NCT07363486Possibly a fitRecruiting

Study of 225Ac-LNC1011 for advanced prostate cancer

Prostate Cancer

Part of Cancer, Kidney & urinary clinical trials.

This trial tests a new radioactive drug called 225Ac-LNC1011 for men with a specific type of advanced prostate cancer that has spread and no longer responds to standard hormone therapy. The goal is to see if it can shrink tumors or slow the disease.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
9 people
Ages
18 years to 90 years
Study type
Interventional

Who can take part

  • You have metastatic castration-resistant prostate cancer (prostate cancer that has spread and is growing despite low testosterone levels).
  • You have tried at least one but no more than two prior chemotherapies (like taxanes) and at least one newer hormone therapy (like abiraterone or enzalutamide).
  • You are between 18 and 90 years old.
  • You have a PSMA PET scan showing high uptake in your tumors (a sign the drug can target them).
  • You have at least one measurable tumor or bone metastasis on scans.
  • Your blood counts, liver, kidney, and clotting function are adequate, and you have not had blood transfusions or growth factors recently.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07562438Recruiting· Phase 2
Lutetium-177 Treatment for Advanced Prostate Cancer

This trial tests a radioactive medication (177Lu-P17-088) designed to target and treat prostate cancer that has spread to other parts of the body and stopped responding to hormone therapy. The medication is guided to cancer cells using a special imaging scan, potentially offering a new treatment option for men who have already tried other standard therapies.

Fuzhou, Fujian
NCT07381582Not yet recruiting· Early Phase 1
Radioactive drug for advanced prostate cancer

This trial tests an experimental radioactive drug that targets a protein called PSMA found on prostate cancer cells. It aims to see if this drug is safe and can shrink tumors in men with advanced prostate cancer that has not responded to hormone therapy or chemotherapy.

Beijing, Beijing Municipality
NCT07581184Recruiting· Phase 1
Targeted Radioactive Therapy for Advanced Prostate Cancer

This Phase 1 trial tests a new radioactive treatment called [225Ac]Ac-AKY-2519 in men with advanced prostate cancer that has spread and stopped responding to hormone therapy. The drug carries radioactivity directly to cancer cells to try to shrink tumors and slow disease progression.

Irvine, California
NCT04886986Recruiting· Phase 1
Testing a targeted radiation pill for advanced prostate cancer

This Phase 1 trial tests a small-molecule treatment that carries radioactive material to help treat prostate cancer that has spread and keeps growing despite standard hormone-blocking treatment. It’s mainly looking to find a safe dose and see how well the approach works in people with limited treatment options.

Brooklyn, New York
NCT06546527Not yet recruiting· Early Phase 1
Study of a radioligand therapy for advanced prostate cancer

This trial tests a new drug (177Lu-PSMA-137) that targets prostate cancer cells with a special molecule to deliver radiation directly to them. It is for men with metastatic castration-resistant prostate cancer whose cancer has progressed after standard treatments like hormone therapy and chemotherapy.

NCT06139575Recruiting· Phase 1/Phase 2
A study of a new drug for advanced prostate cancer

This trial tests a radioactive drug called Lu 177 JH020002 for men with advanced prostate cancer that has spread and stopped responding to hormone therapy. The drug targets a protein on cancer cells to deliver radiation directly, possibly slowing the disease.

Hefei, Anhui

Hear when a new Prostate cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.