Targeted Radioactive Therapy for Advanced Prostate Cancer
Part of Cancer, Kidney & urinary clinical trials.
This Phase 1 trial tests a new radioactive treatment called [225Ac]Ac-AKY-2519 in men with advanced prostate cancer that has spread and stopped responding to hormone therapy. The drug carries radioactivity directly to cancer cells to try to shrink tumors and slow disease progression.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Diagnosed with prostate cancer (adenocarcinoma) confirmed by biopsy or cell sample
- Cancer has spread to other parts of the body and is no longer responding to hormone-lowering treatment
- Testosterone levels lowered to castrate levels (below 50 ng/dL) through surgery or medication
- Cancer has grown on recent scans or PSA blood tests despite previous treatment
- Good overall health and able to care for yourself with minimal assistance (ECOG 0–1)
- Had previous treatments with certain drugs, but not too many (limits on hormone inhibitors and chemotherapy)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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