Blood thinner comparison for heart patients at high bleeding risk
Treatments studied
Part of Heart & circulation clinical trials.
This trial compares two blood thinners (bivalirudin and heparin) during a procedure to open blocked heart arteries (PCI) in patients with a recent heart attack or unstable angina who also have a high risk of bleeding. The goal is to see which drug works better and is safer for patients like you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have unstable angina or a recent heart attack (more than 48 hours ago) and need a stent procedure (PCI).
- You are at high risk for bleeding according to standard criteria (e.g., age over 75, low red blood cell count, or on blood thinners).
- You have not had heart surgery or a stent in the last 6 months.
- You are not in cardiogenic shock and no planned bypass surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares two ways to choose blood thinners after a heart attack in people at high risk for bleeding. One way uses a genetic test to guide the choice, while the other uses a different approach.
This trial is testing whether a newer type of blood thinner (called a NOAC) can be used safely right after a heart attack or related event, in addition to the standard two antiplatelet medicines. It focuses on patients who have higher risk signs, like elevated D-dimer levels or a higher PARIS risk score, to see if this approach is safe and effective at preventing future heart problems.
This study looks at the best time to give a standard blood thinner (heparin) during a heart procedure called angioplasty, which opens blocked heart arteries through a wrist artery. It may help reduce bleeding or clotting risks.
This trial tests whether taking just one blood thinner (clopidogrel) is as safe and effective as taking two (clopidogrel plus aspirin) for older adults or people at high bleeding risk who have had a drug-coated balloon procedure to open blocked heart arteries.
This trial compares two blood-thinning medicines (bivalirudin vs. heparin) given during angioplasty to people who've already had a clot-buster for a heart attack. The goal is to see which one works better to keep arteries open without increasing bleeding risk.
This trial studies which blood-thinner (antiplatelet) strategy is safest and most effective for people at high risk of bleeding after a procedure called PCI. It also looks at longer-term outcomes and whether adjusting treatment can improve safety without losing heart protection.
Hear when a new Percutaneous Coronary Intervention trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.