Clin2
NCT07389629Possibly a fitRecruiting

Combination therapy before surgery for kidney cancer

Iparomlimab and TuvonralimabClear Cell Renal Cell CarcinomaNeoadjuvant Therapy

Part of Cancer, Kidney & urinary, Women’s health & pregnancy clinical trials.

This trial tests a new drug combination given before surgery for kidney cancer that is early stage but hard to operate on. The goal is to shrink the tumor and make surgery easier.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
25 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • Clear cell kidney cancer confirmed by biopsy before surgery.
  • Tumor stage T1N0M0 or T2N0M0 with a R.E.N.A.L. score of 10 or higher, meaning the tumor is complex to remove.
  • Age between 18 and 80 years old.
  • Willing to have kidney-sparing surgery.
  • Good overall health with an ECOG score of 0 or 1 (fully active or slightly limited).
  • No spread to lymph nodes, no blood vessel involvement, and no metastasis.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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