Clin2
NCT07391241Possibly a fitRecruiting

Pudafensine for vulvar pain study

Vulvodynia

Part of Women’s health & pregnancy clinical trials.

This trial tests a new medicine called pudafensine to see if it safely reduces pain in women with vulvodynia, a condition that causes pain when the vulvar area is touched.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
24 people
Ages
18 years to 65 years
Study type
Interventional

Who can take part

  • You have been diagnosed with vulvodynia (pain in the vulvar area, especially when touched).
  • Your vulvar pain is not caused by an infection like yeast or herpes.
  • Your vulvar pain is not caused by a skin condition like lichen sclerosus.
  • You do not have cancer or a history of cancer in the vulvar area.
  • You do not have nerve damage or a nerve condition causing the pain.
  • You do not have other pelvic pain conditions like endometriosis, interstitial cystitis, or pelvic floor problems.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07257029Recruiting· Phase 2
Ketotifen Cream for Vulvar Pain

This trial tests a topical cream called ketotifen for treating a type of vulvar pain (secondary provoked vestibulodynia). The cream may help reduce pain at the vaginal opening, and you would apply it daily for several months.

Washington D.C., District of Columbia
NCT07862400Not yet recruiting· Phase 2
Low-dose naltrexone for vulvar pain

This study tests a low dose of naltrexone (a pill that may help reduce pain) for vulvodynia, a condition causing long-lasting pain in the vulvar area. It aims to see if this treatment can ease the pain and improve quality of life.

Jacksonville, Florida
NCT05343182Recruiting
Compare two surgical techniques for vestibular pain

This study compares two different surgery techniques for people with long-lasting, touch-triggered pain at the vaginal entrance (“vestibule”). You might be offered one of the surgical approaches and you’ll complete pain testing and follow-up measurements to see which technique works best.

Portland, Oregon
NCT06660212Recruiting
Pelvic health rehab study for women with pain

This study tests whether biomodulation therapy combined with pelvic floor rehabilitation can help women with certain types of pelvic pain. It is for premenopausal women who were born female and are experiencing provoked vestibulodynia (pain at the vaginal opening) with or without vaginismus (tightness).

Ottawa, Ontario
NCT06337448Not yet recruiting
Light therapy for vulvodynia pain

This trial tests whether a special light device (LED) applied to the vulvar area can reduce pain and discomfort from vulvodynia. If you have vulvodynia, this treatment might be a non-invasive way to help manage your symptoms.

Salvador, Estado de Bahia
NCT07260825Not yet recruiting· Phase 2/Phase 3
Hormone cream for vulvodynia pain

This trial compares two hormone creams for women with vulvodynia (chronic pain at the opening of the vagina). One group will use a cream with both testosterone and estrogen, and the other group will use a cream with estrogen alone, to see which better reduces pain during sex or tampon use.

Cincinnati, Ohio

Hear when a new Vulvodynia trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.