Muscle preservation during weight loss with GLP-1 drugs
Part of Hormones & metabolism clinical trials.
This trial tests a special medical food to help keep muscle mass while losing weight with GLP-1 medications like liraglutide, semaglutide, or tirzepatide. It's for adults with obesity or overweight with related health issues.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old
- You have a BMI of 30 or higher, or a BMI of 27 or higher with a weight-related health problem (like high blood pressure, prediabetes, or sleep apnea)
- You have just started (or will start within 2 weeks) a GLP-1 weight-loss drug such as liraglutide, semaglutide, or tirzepatide
- You are willing to adjust your diet to include specific protein levels based on your ideal body weight
- You do not have diabetes (type 1 or 2), severe kidney problems, or active cancer
- You are not pregnant or breastfeeding, and you agree to avoid certain amino acid or HMB supplements unless you stop them 15 days before starting
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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