Clinical trials
Obesity & Overweight clinical trials
Below are recruiting obesity & overweight clinical trials, each written for real people, not researchers. We’re tracking 489 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07595549RecruitingPhase 3
Testing Berobenatide for Weight Loss in Overweight Adults
This study tests a new medicine called berobenatide to help people with overweight or obesity lose weight. The medicine may also help improve related health conditions like high blood pressure, high cholesterol, or type 2 diabetes.
Canoga Park, CaliforniaAges 18 years+ - NCT05038683Recruiting
Child weight program study: new treatment vs usual care
This trial tests a structured obesity treatment program for children compared with the usual (conventional) approach. It may help your child get support to improve healthy weight habits.
Ballerup Municipality, BallerupAges 6–11 - NCT05770570RecruitingPhase 2
Diet and activity texting support for Mexican American drivers
This Phase 2 study tests a structured program using texts and recordings to help people improve diet and physical activity for weight loss. It focuses on specific Spanish-speaking groups and also includes a separate track for taxi/FHV drivers.
New York, New YorkAges 21 years+ - NCT07575932RecruitingPhase 2
Testing New Weight Loss Medications PF-08653945 and PF-08653944
This study tests two new experimental medications designed to help adults lose weight and improve weight-related health conditions like high blood pressure and sleep apnea. Participants will take one of these medications to see if it's safe and effective.
Chandler, ArizonaAges 18 years+ - NCT07009171RecruitingPhase 2
Testing KDS2010 for weight loss in overweight or obese adults
This study tests a new medication called KDS2010 for people who are overweight or have obesity. The goal is to see if it helps with weight loss when combined with diet and exercise.
Suwon, Gyeonggi-doAges 18 years+ - NCT07227051Recruiting
Phone app and fitness tracker for weight loss study
This study tests a smartphone app and fitness tracker to help people lose weight by monitoring their diet and activity. Participants get feedback and support through the app.
Milwaukee, WisconsinAges 18 years+ - NCT07342855Recruiting
Healthy lifestyle program for children with obesity
This trial looks at how a community healthy lifestyle program helps children with obesity. Your family would join a program that supports healthy eating and physical activity, and researchers will track your child's progress.
Dallas, TexasAges 6–14 - NCT07578584RecruitingPhase 1
Safety study of NNC0497-0040 in healthy and overweight adults
This early-stage study tests a new investigational medication in three groups: healthy adults with normal weight, adults who are overweight or obese, and men with type 1 diabetes who are also overweight. The research aims to understand how safe the medication is and how the body processes it.
NeussAges 18–55 - NCT07662122RecruitingPhase 2
Testing a new weight loss medication in adults with obesity or overweight
This trial tests an investigational drug called BI 3034701 to see if it helps people lose weight. It is for adults who are obese or overweight with at least one weight-related health problem.
Birmingham, AlabamaAges 18–74 - NCT07738614RecruitingPhase 1
Testing an investigational weight loss medicine for adults with overweight or obesity
This study tests an experimental medicine (eloralintide) to see if it can help people with overweight or obesity lose weight without having diabetes. The medicine works by affecting hormones that help control appetite and body weight.
San Antonio, TexasAges 18–65 - NCT07628127RecruitingPhase 1
Study of VRB-103 with or without ecnoglutide for weight loss
This early-stage trial tests two experimental medications—VRB-103 alone or combined with ecnoglutide—to help people with overweight or obesity lose weight. Both drugs are designed to help control appetite and may offer a new treatment option if you qualify.
MelbourneAges 18–60 - NCT07566390RecruitingPhase 1
Testing a new weight-loss medicine in healthy adults
This early-stage study tests a new experimental medicine (NNC0113-5840) to see how it works in people who are overweight or have obesity. Researchers want to understand how the body processes this medicine and whether it's safe before testing it more widely.
Glendale, CaliforniaAges 18–55 - NCT07437079RecruitingPhase 1
Testing a new weight-loss medicine in healthy people
This study tests a new medicine (NNC6989-0001) for people who are overweight or have obesity. It checks if the medicine is safe and how the body handles it. If eligible, you would receive the study drug and be monitored closely.
Lenexa, KansasAges 18–55 - NCT07665879RecruitingPhase 1
Study of an experimental drug for people with overweight or obesity
This trial tests an experimental drug (Eloralintide) to see if it can help with weight management. It is for people who have a body mass index (BMI) between 25 and 45 and stable weight.
NeussAges 18–70 - NCT05912621RecruitingPhase 2
Tirzepatide for fat-related body dysfunction in overweight adults
This Phase 2 study tests whether tirzepatide can improve how your body handles fat (especially in people with overweight or obesity) and reduce fat-related “lipotoxicity.” It may help with body fat function and related health markers, but you must meet specific health and medication rules.
Palo Alto, CaliforniaAges 18–70 - NCT06143956RecruitingPhase 2
Weight loss treatments for adults with obesity
This clinical trial tests new treatments for adults who are overweight or have obesity. The goal is to help people lose weight and improve their health.
Chandler, ArizonaAges 18–75 - NCT07075146RecruitingPhase 3
Comparing two HIV treatments for people with overweight or obesity
This trial compares two different daily pill combinations for people newly starting HIV treatment who are overweight or have obesity. It aims to see which one works better for controlling the virus and managing weight.
Mexico CityAges 18–70 - NCT07245771RecruitingPhase 1/Phase 2
Weight loss study testing a new drug alone or with tirzepatide
This trial tests an experimental drug called RN3161 to see if it helps with weight loss in people with overweight or obesity. It can be taken alone or with another weight-loss medication (tirzepatide).
Melbourne, VictoriaAges 18–65 - NCT07395687RecruitingPhase 2
Study of UBT251 for people with overweight or obesity
This trial tests different doses of UBT251, a new medicine, to see how well it helps people lose weight. It may be an option if you have overweight or obesity and meet certain age and BMI requirements.
Cypress, CaliforniaAges 18–65 - NCT07411560RecruitingPhase 1
Weekly injections for stomach side effects in overweight people
This study tests two weekly hormone injections (GIP and amylin) to see how they affect stomach-related side effects in people who are overweight or obese. Researchers want to understand if these hormones can help manage weight or related symptoms.
Harrow, MiddlesexAges 18–64 - NCT07331974Recruiting
A trial of Akkermansia for weight loss in overweight adults
This trial tests a supplement containing Akkermansia bacteria to see if it helps adults who are overweight or obese lose weight. It may be an option if you have not taken weight loss medications recently and are already trying to manage your weight with diet and exercise.
Guangzhou, GuangdongAges 18–60 - NCT07557953RecruitingPhase 1
How cagrilintide affects hunger and eating in overweight adults
This early-stage study tests a new medication called cagrilintide to see how it influences appetite and food intake in adults with overweight or obesity. Researchers want to understand if this drug could help people feel fuller and eat less.
BerlinAges 18–64 - NCT07589608RecruitingPhase 2
Weight Loss Study With Two New Injectable Medications
This study tests two new injectable drugs (macupatide and eloralintide) alone or together to help adults with obesity or excess weight lose weight. The goal is to see if these medications are safe and effective for weight management.
Chandler, ArizonaAges 18–75 - NCT07597018RecruitingPhase 1
Comparing Blood Levels of Cagrilintide Versions in Adults With Overweight
This early-stage study tests different formulations of cagrilintide, a new medication, to see how the body absorbs and processes each version. Cagrilintide may help with weight management. Researchers will measure blood levels after you receive multiple doses.
BerlinAges 18–64
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Obesity & Overweight trials by city
Studies with a site in or near these metro areas.
Obesity & Overweight trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for obesity & overweight?
- Yes. Clin2 currently lists 489 recruiting obesity & overweight studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity & overweight trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity & overweight trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.