Exercise and diet to prevent muscle loss on GLP-1 meds
Treatments studied
Part of Brain & nervous system, Hormones & metabolism clinical trials.
This study tests whether a 12-week program of exercise and personalized nutrition can help adults who are obese and taking GLP-1 weight-loss medications maintain muscle and bone while losing fat. It aims to improve strength, fitness, and overall function during treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 40 and 55 years old.
- Your body mass index (BMI) must be over 30, which is in the obese range.
- You must have a high body fat percentage: over 30% for men and over 40% for women.
- Your waist-to-hip fat ratio must be above 1.0.
- You must be eligible to start or continue GLP-1 therapy, but you must not have type 2 diabetes.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a special medical food to help keep muscle mass while losing weight with GLP-1 medications like liraglutide, semaglutide, or tirzepatide. It's for adults with obesity or overweight with related health issues.
This study looks at whether certain dietary supplements can help preserve muscle mass while you are taking a GLP-1 medication for weight loss. You would take the supplements or a placebo for a period while continuing your GLP-1 treatment, and the researchers will measure changes in your muscle and strength.
This study tests whether adding resistance exercise to a new weight-loss medication helps women preserve muscle while losing weight. It may be an option for women who want to protect their muscle mass during treatment.
This study tests a 12-week digital strength training program for women aged 40–54 who have recently started taking a GLP-1 medication for weight management. The program uses a smartphone app to guide bodyweight exercises at home, with the goal of preserving muscle while losing weight.
This trial compares different ways to keep weight off after you've lost weight using a GLP-1 medication, like semaglutide or tirzepatide. It tests reducing your GLP-1 dose and adding other weight loss medications to help maintain your progress.
This study looks at whether exercise can help prevent muscle loss in people taking GLP-1 medications (like Wegovy, Ozempic, or Mounjaro) for weight loss. It may help you keep your muscles strong while you lose weight.
Hear when a new GLP-1 trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.