Clin2
NCT07393919Possibly a fitNot yet recruiting

Stopping antidepressants for depression in remission

Depression - Major Depressive Disorder

Part of Mental health clinical trials.

This trial compares different ways to safely stop taking an antidepressant when your depression is in remission. It aims to find the best strategy to avoid withdrawal symptoms and keep you well.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
150 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have been diagnosed with depression (a single episode or repeated episodes).
  • You are currently taking an antidepressant from a specific list (SSRI, SNRI, TCA, or vortioxetine) for at least 6 months, with a stable dose for the last 2 months.
  • Your depression is in remission, meaning you have low scores on depression and anxiety questionnaires and have not had moderate-to-severe symptoms in the past 6 months.
  • Your doctor agrees that stopping your antidepressant is a good idea, and you are unsure which way to stop is best.
  • You are not pregnant or planning to become pregnant, and you do not have certain other mental health conditions (like bipolar disorder or schizophrenia).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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