Clin2
NCT07810738Possibly a fitNot yet recruiting

Computer-guided treatment selection for older adults with tough depression

Late Life Treatment Resistant DepressionDepression - Major Depressive DisorderTreatment Resistant Depression

Part of Mental health clinical trials.

This study tests a computer-based tool to help choose the next medication for older adults with stubborn depression. It may help match you with a treatment (aripiprazole or bupropion) that is more likely to work for you.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
300 people
Ages
60 years and older
Study type
Interventional

Who can take part

  • You must be 60 years old or older.
  • You must have major depression that hasn't improved with at least two earlier treatments.
  • You need to be taking an antidepressant at a steady dose for at least 4 weeks before starting.
  • You cannot have dementia, bipolar disorder, schizophrenia, or a recent serious substance use problem.
  • You must not be at high risk for suicide right now.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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