Psychotherapy with esketamine nasal spray for suicidal thoughts
Part of Mental health clinical trials.
This study tests combining a specific type of therapy (BCBT-SP) with esketamine nasal spray to help people with treatment-resistant depression who are having ongoing suicidal thoughts. The goal is to see if this combination can reduce suicidal ideation more effectively than either treatment alone.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old.
- You have been diagnosed with treatment-resistant depression (depression that hasn't improved with standard antidepressants).
- Your doctor has prescribed esketamine nasal spray for you.
- You are currently having suicidal thoughts (score of 4 or more on a standard scale).
- You are an outpatient able to attend all treatment sessions at UCSD.
- You do not have a cardiac pacemaker, history of seizures, or metal implants in your head.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether ketamine (a medication) combined with a specific type of therapy called DBT can help people with treatment-resistant depression and borderline personality disorder who are having thoughts of suicide. You would receive ketamine infusions alongside structured therapy sessions over 6 months.
This study tests if ketamine can help reduce suicidal thoughts in people with major depression. You'll receive ketamine treatment and be monitored closely.
This trial tests if a single dose of ketamine can quickly reduce suicidal thoughts in people who come to the emergency department. If you are having active suicidal thoughts and need inpatient care, you may be able to join.
This study tests esketamine nasal spray versus a placebo in adults with depression that has not improved after trying at least two other antidepressants. It aims to see if the spray can help when standard pills have not worked.
This trial tests if adding a type of talk therapy called integration therapy helps esketamine work better for people with depression that hasn't improved with other treatments. You'll receive esketamine, and some people also get guided sessions to reflect on their experiences.
This study tests whether esketamine, a nasal spray for depression, can help adults whose depression has not improved with at least two other antidepressants. Participants continue their current treatment while receiving esketamine.
Hear when a new Suicidal Ideation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.