Ketamine plus therapy for depression with suicidal thoughts
Treatments studied
Part of Mental health clinical trials.
This study tests whether ketamine (a medication) combined with a specific type of therapy called DBT can help people with treatment-resistant depression and borderline personality disorder who are having thoughts of suicide. You would receive ketamine infusions alongside structured therapy sessions over 6 months.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18–70
- Diagnosed with borderline personality disorder (a pattern of unstable relationships and self-image)
- Diagnosed with depression or bipolar disorder that is currently moderate to severe
- Have had significant suicidal thoughts in the past two weeks
- Have tried at least two different antidepressant medications without adequate improvement
- Willing to commit to 6 months of DBT (dialectical behavior therapy, a structured weekly therapy)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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