Clin2
NCT07396324Possibly a fitRecruiting

A new drug before surgery for HR+ HER2- breast cancer

HR-positive/HER2-negative Breast Cancer

Treatments studied

Part of Cancer clinical trials.

This trial tests whether the drug QL1706, given before surgery, can help treat hormone receptor positive and HER2-negative breast cancer. It is for people who have not yet had cancer spread to other parts of the body.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
55 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older
  • You have hormone receptor positive, HER2-negative breast cancer (confirmed by biopsy)
  • You have at least one tumor that can be seen on a scan or exam
  • You feel well enough to do daily activities (ECOG score 0 or 1)
  • Your liver, kidneys, and other organs are working well enough
  • You are not pregnant, not breastfeeding, and willing to use birth control during the study

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07180160Recruiting· Phase 2
A study of QL1706 for HR-positive, HER2-negative breast cancer

This trial tests a new drug combination (iparomlimab and tuvonralimab, also called QL1706) for people with advanced breast cancer that is hormone receptor-positive and HER2-negative. It may be an option if standard treatments have stopped working.

Shanghai
NCT07867392Recruiting· Phase 2
New drug combo before surgery for stomach cancer

This study tests a combination of two immunotherapy drugs plus chemotherapy before surgery for people with locally advanced stomach or gastroesophageal junction cancer. The goal is to see if this treatment can shrink the tumor and improve outcomes.

Shanghai, Shanghai Municipality
NCT07197697Not yet recruiting· Phase 2
Immunotherapy and chemotherapy before surgery for HR-positive, HER2-negative breast cancer

This trial tests a new combination of immunotherapy drugs (iparomlimab and tuvonralimab) plus chemotherapy given before surgery for a certain type of breast cancer. The goal is to see if this approach can shrink tumors more effectively and improve outcomes.

NCT07782840Not yet recruiting· Phase 2
Immunotherapy plus hormone therapy for breast cancer that did not shrink after chemotherapy

This trial tests a new immunotherapy drug (QL1706) combined with hormone therapy for breast cancer that is hormone receptor positive and HER2 negative, but did not respond well to initial chemotherapy. The goal is to see if this combination can shrink tumors before surgery and potentially improve outcomes.

NCT07186868Not yet recruiting
A new treatment option for advanced cervical cancer that has stopped responding to immunotherapy

This trial tests a new drug called QL706 combined with chemotherapy, with or without another drug called bevacizumab, for people with cervical cancer that has returned or spread and no longer responds to prior immunotherapy. The goal is to see if this combination can help shrink tumors or slow the cancer's growth.

NCT06967103Recruiting· Phase 2
New drug before breast cancer surgery

This trial tests a new drug, QL1706, given alongside chemotherapy before surgery for a certain type of breast cancer. It aims to see if this combination helps shrink tumors before they are removed.

Zhengzhou

Hear when a new HR-positive/HER2-negative Breast Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.