Saliva changes with braces vs clear aligners
Part of Mouth & dental clinical trials.
This study looks at how saliva (spit) changes during orthodontic treatment with traditional braces or clear aligners like Invisalign. It may help your orthodontist understand how these treatments affect your mouth's natural protection and comfort.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You are getting traditional braces or clear aligners
- You have not taken antibiotics or any other medications that affect your spit in the last 3 months
- You do not smoke, vape, or use e-cigarettes
- You do not have conditions like Sjogren's syndrome, diabetes, or chronic kidney disease
- You have been in orthodontic treatment for at least 3 months
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study checks the safety and structure of Invisalign clear aligners used during orthodontic treatment. It looks for any harmful substances released from the aligners.
This study tests three ways to clean your clear aligners—brushing, a special mouth rinse, and a UV device—to see which one keeps your mouth and gums healthiest during treatment.
This study compares clear aligners and traditional braces to see how each affects your jaw muscles. It will use a simple, painless test (surface electromyography) to measure muscle activity, helping you understand which option might be better for you.
This study looks at how braces (orthodontic treatment) change the bacteria and proteins in your mouth. Healthy volunteers who have never had dental work or cavities are needed to provide saliva samples before and during treatment.
This study looks at whether stress markers in saliva are linked to how severe a person's dental misalignment (malocclusion) is. It may help doctors understand the impact of alignment problems on the body's stress response.
This study looks at whether using specific toothbrushes in daily life can improve dental gum and tooth health for teens with fixed braces. It may help by testing simple at-home brushing routines that could reduce gum problems during orthodontic treatment.
Hear when a new Orthodontic Treatment trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.