Clinical trials
Orthodontic Treatment clinical trials
Below are recruiting orthodontic treatment clinical trials, each written for real people, not researchers. We’re tracking 29 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07513792Recruiting
3D imaging to prevent gum shrinkage during clear aligner treatment
This study tests whether a special 3D imaging tool helps protect your gums from pulling back (receding) while straightening your teeth with clear aligners. Gum recession can expose tooth roots and cause sensitivity, so the trial is exploring whether better visualization during treatment planning prevents this problem.
Liège, LiegeAges 18 years+ - NCT07217756Recruiting
How weight affects braces treatment in teens
This study looks at how having a higher BMI (body mass index) affects treatment with braces during the teenage years. It will compare results between teens with normal weight and those who are overweight to see if there are any differences in how long or how well braces work.
Rochester, New YorkAges 12–18 - NCT07325643Recruiting
Toothpaste and mouthwash to prevent white spots during braces
This study tests if a special toothpaste and mouthwash can stop white spots from forming on teeth while you have braces. It is for people starting orthodontic treatment who have healthy teeth and gums.
BaghdadAges Any age - NCT07107100Recruiting
Comparing two types of retainers after braces
This study compares two types of retainers (a wire that keeps teeth in place) after braces are removed: one that is directly bonded to the teeth and one that is made indirectly. It looks at which type keeps gums healthy, lasts longer, and how likely it is to break.
Karachi, SindhAges 13–40 - NCT05733676Recruiting
MI Paste Plus vs resin for white spots after braces
This trial compares two tooth treatments to see which one works better for “white spot” areas that can appear after braces come off. If you have mild plaque buildup and at least one white spot on front teeth, you may be eligible to test one of these options and improve tooth surface healing.
Edmonton, AlbertaAges 12–21 - NCT07814716Recruiting
Dental bands for treating soft enamel in children's back teeth
This study tests whether special metal bands around children's back teeth help protect teeth with soft, weak enamel (from a condition called hypomineralization) and improve the success of fillings. It compares this approach to standard dental care to see which works better.
Natal, Rio Grande do NorteAges 5–10 - NCT07763808RecruitingPhase 2/Phase 3
Gum surgery for receding gums after braces
This study tests different surgical methods to repair receding gums that can happen after orthodontic treatment. If you have gum recession and are otherwise healthy, this trial may help improve your gum health and appearance.
BakuAges 18–70 - NCT07747350Recruiting
Laser vs pain pills for braces pain in Malay women
This study compares a low-level laser treatment with standard painkillers to see which works better for reducing pain from getting braces. It is for Malay women aged 18-33 who have never had braces and are generally healthy.
Kota Bharu, KOTA BHARUAges 18–33 - NCT07091422Recruiting
Testing a new brace glue: does it hold better?
This trial tests a new no-etching glue for braces. Half of your mouth will get the new glue, the other half a standard glue, to see which one holds the brackets better over a year.
Baltimore, MarylandAges 14–35 - NCT05038865Recruiting
How jaw alignment affects teens’ quality of life
This study compares how different types of bite/jaw alignment affect adolescents’ daily comfort and oral-health-related quality of life. It’s mainly done by asking teens to complete questionnaires and comparing groups with and without malocclusion.
Malmö, Skåne CountyAges 12–19 - NCT06824493Recruiting
How Braces Affect Mouth Bacteria and Saliva
This study looks at how braces (orthodontic treatment) change the bacteria and proteins in your mouth. Healthy volunteers who have never had dental work or cavities are needed to provide saliva samples before and during treatment.
Xi'an, ShaanxiAges 6–18 - NCT06751979Recruiting
Probiotics for people with braces
This trial tests if a probiotic can improve oral health for people with braces. It might help reduce plaque buildup around brackets and wires.
AarhusAges 10 years+ - NCT07445555Recruiting
Gum Recession Study: Braces vs. No Braces
This study looks at gum recession (when gums pull away from teeth) in adults, comparing those who had braces in the past to those who did not. It aims to understand if orthodontic treatment affects gum health.
LeuvenAges 18 years+ - NCT07288853Recruiting
Can a smartphone app help teens with braces keep cleaner teeth?
This trial tests whether a smartphone app with reminders can help teenagers with braces keep their teeth and gums cleaner. If you're getting braces and have a smartphone, you might be eligible.
Kuantan, PahangAges 12–18 - NCT06948162Recruiting
Dental MRI for routine dental care
This study tests whether a special MRI machine can take detailed images of teeth and jaws for routine dental care. It may help find problems without using X-rays.
Minneapolis, MinnesotaAges 18 years+ - NCT05710952Recruiting
Orthodontic braces study and how they affect jaw joints
This study looks at whether multi-attachment orthodontic treatment (either on the front or back of teeth) changes the temporomandibular joint, which is the jaw joint. The researchers will assess your jaw joint using a tool called Modjaw.
MontpellierAges 18 years+ - NCT06685016Recruiting
Study of dental health after IPR with clear aligners
This study looks at how the teeth and gums are doing after a common orthodontic step called IPR (a slight smoothing between teeth) in people wearing clear aligners. It will help understand if this procedure keeps your mouth healthy.
NaplesAges 17–100 - NCT07567105Recruiting
Long-term stability of open-bite orthodontic treatment
This study looks at whether orthodontic treatment for anterior open bite (a gap between upper and lower front teeth when biting down) stays stable over time. The researchers want to understand what helps the correction last.
VantaaAges Any age - NCT07264127Recruiting
I-arch system for early orthodontic treatment
This study tests a new orthodontic tool, the I-arch system, for straightening the lower front teeth when they are moderately crowded. It aims to see how well the I-arch works during the first stage of braces treatment.
KarbalaAges 12 years+ - NCT07234149Recruiting
Comparing tooth color change and removal time for two attachment materials
This study compares two types of tooth-colored materials used for the small bumps (attachments) placed on teeth during clear-aligner treatment. Researchers want to see which material causes less tooth staining and is easier for the dentist to remove.
Kirkuk, Kirkuk GovernorateAges 18–40 - NCT07155343RecruitingEarly Phase 1
Comparing two types of glue for braces in teens and adults
This early-phase trial tests if a newer, faster-setting glue (bulk-fill composite) works as well as the standard glue for attaching braces. It's for people aged 13 to 40 who are starting or continuing fixed braces treatment.
Karachi, SindhAges 13–40 - NCT07097714Recruiting
Collagen scaffold with gum surgery to improve orthodontic results
This trial tests if a special collagen scaffold placed during gum surgery can improve orthodontic treatment for people with thin gums. It may help protect the gums and bone during teeth straightening.
Novosibirsk, Novosibirsk OblastAges 18–50 - NCT06315348Recruiting
Gum shaping during braces with a vibration tool
This trial tests a new, less invasive surgical technique (using a special tool that vibrates, not a scalpel) to help reshape the gums while straightening teeth with braces. It is for people who need braces for mild to moderate crowding and have healthy gums.
MadridAges 16–70 - NCT07752498Enrolling by invitation
Long-term results from twin block treatment
This study checks whether the results from an earlier treatment with the Twin Block appliance, which corrects bite problems, hold up over time. It looks at how stable the teeth and jaw remain years after treatment.
Jönköping, Jönköping CountyAges Any age
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Common questions
- Are there clinical trials for orthodontic treatment?
- Yes. Clin2 currently lists 29 recruiting orthodontic treatment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a orthodontic treatment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a orthodontic treatment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.