Stem cell injection to prevent severe mouth sores in transplant
Treatments studied
Part of Digestive system, Mouth & dental clinical trials.
This trial is testing a single injection called Amimestrocel to prevent severe mouth sores in people getting a stem cell transplant. The study is for adults who are receiving high-dose conditioning with total body irradiation or melphalan, which often cause painful mouth inflammation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You are about to have a stem cell transplant from a donor, using high-dose chemo or radiation to prepare your body.
- Your pre-transplant plan includes total body irradiation or the drug melphalan.
- You feel well enough to do everyday activities (ECOG 0 or 1).
- Your heart, liver, and kidneys are working well enough.
- You have no allergy to stem cells or the study injection, and no recent history of cancer or serious infection.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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