Dopamine signals in health and Parkinson's
Part of Brain & nervous system clinical trials.
This study uses MRI scans to look at dopamine signals in the brain. The goal is to understand how Parkinson's affects these signals.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 35 years old.
- You have either diagnosed Parkinson's (stiffness type) or you are a healthy volunteer.
- You are not pregnant, not breastfeeding, and able to have an MRI (no metal implants, claustrophobia, etc.).
- You do not take certain medications like antipsychotics or gabapentinoids.
- You do not have severe depression or other neurological conditions besides Parkinson's.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study uses brain scans to understand Parkinson's disease. It compares people with Parkinson's to healthy volunteers to learn how the brain changes.
This study is building a large, detailed group of people—some with Parkinson’s and some at higher risk—to understand early changes over time. It uses brain imaging (DaTscan SPECT), sometimes spinal fluid tests (lumbar puncture), and genetic information to help researchers better measure disease and develop future treatments.
This study uses a special 7‑Tesla MRI brain scan to measure tiny chemical (metabolite) differences in specific deep brain areas. It compares newly diagnosed, early-stage Parkinson’s patients who are not on Parkinson medication with healthy volunteers.
This research uses brain imaging scans to study how a chemical messenger in the brain (called noradrenaline) changes as people age and in Parkinson's disease. The goal is to better understand how this brain system works and may help develop future treatments.
This study uses a special test to look at dopamine levels in the brain of people with Parkinson's disease. It may help doctors understand the disease better and could lead to better treatments.
This study uses a special PET scan to look at inflammation in the brain of people with Parkinson's disease or those at risk for it. The goal is to better understand the disease and possibly find new ways to track its progression.
Hear when a new Parkinson trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.