Psilocybin treatment for pain after trauma surgery
Treatments studied
Part of Brain & nervous system, Pain clinical trials.
This trial tests whether a single dose of psilocybin (a psychedelic substance) can help reduce pain and improve recovery in adults who have just had surgery for a traumatic injury. It is given in the hospital and patients are monitored closely for 8 hours.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 65 years old.
- You had surgery for a traumatic injury and are in the intensive care unit (ICU) within 3 days after surgery.
- You are not currently using certain other psychoactive medications (like SSRIs, antipsychotics, or ketamine) and can stop them for 30 days before the study dose.
- You do not have serious heart, brain, liver, or mental health conditions (such as uncontrolled high blood pressure, head injury, schizophrenia, or bipolar disorder).
- You can stay in your room and not smoke for the 8-hour study period.
- You are not pregnant, breastfeeding, or of childbearing potential without using effective birth control.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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