Clinical trials
Pain Management clinical trials
Below are recruiting pain management clinical trials, each written for real people, not researchers. We’re tracking 347 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07149870Recruiting
Pain management team for veterans with chronic pain
This study is testing whether a team-based pain management approach helps veterans with chronic pain and long-term opioid use. It aims to improve function and safety by addressing opioid concerns.
Birmingham, AlabamaAges 18 years+ - NCT06878014RecruitingPhase 4
Morphine for pain relief after hip replacement surgery
This trial tests different doses of morphine given during spinal anesthesia to find the safest and most effective way to control pain after hip replacement surgery. If you are having a total hip replacement, you may be able to join.
Sosnowiec, Silesian VoivodeshipAges 18–75 - NCT06001749RecruitingPhase 2
Psilocybin for cancer pain study
This trial tests whether psilocybin (a psychedelic drug) can help with severe cancer pain. You may qualify if your pain is high despite strong medications and you are willing to be monitored closely.
Boston, MassachusettsAges 18 years+ - NCT05563792Recruiting
Non-drug options for managing chronic pain
This study tests non-drug treatments for chronic pain in the back, neck, or joints. It aims to help people manage pain and improve daily function without relying on medications.
Indianapolis, IndianaAges 18 years+ - NCT04004286Recruiting
Pain registry and blood sample biobank for eligible service members
This trial is building a pain registry biobank to learn more about pain and how different people experience it. If you’re eligible for care in the Military Healthcare System and can consent, you may be able to contribute your information for future research.
San Diego, CaliforniaAges 18–80 - NCT07562412Recruiting
Audio Mindfulness for Quick Pain Relief
This study tests whether listening to brief guided mindfulness audio recordings can help reduce acute (sudden, short-term) pain. Researchers will see how different amounts of listening affect pain levels.
Tallahassee, FloridaAges 18 years+ - NCT06381063RecruitingPhase 3
Anti-inflammatory for heart surgery
This trial is testing whether a non-steroidal anti-inflammatory drug (NSAID) given during heart surgery can reduce complications. It's for people having planned open-heart surgery with a heart-lung machine.
AmiensAges 18 years+ - NCT06795243Recruiting
Physical therapy for endometriosis and exercise adherence
This study tests whether physical therapy (exercise for your muscles) can help with endometriosis symptoms and how well people stick with the program. If you have endometriosis and can do light strength exercises, you may be able to join.
SevilleAges 18 years+ - NCT07032350Recruiting
Pain management app for dementia caregivers
This study tests a mobile app that helps family caregivers of people with dementia manage their loved one's chronic pain. It aims to see if the app is easy to use and helpful for caregivers.
Iowa City, IowaAges 18–100 - NCT07179016Recruiting
Acupressure for chronic pain in rural areas
This trial tests if a self-managed acupressure program can help people living in rural areas manage long-term muscle or joint pain, like neck, back, or knee pain. You would learn to press small seeds on your ear to ease pain.
Columbia, South CarolinaAges 18–85 - NCT07332377Recruiting
mHealth pain self-management for cancer survivors
This study tests a mobile health (smartphone) program that helps you manage pain after cancer treatment. It’s for people who have finished treatment and are in remission but still have cancer- or treatment-related pain.
Richmond, VirginiaAges 18 years+ - NCT06467747Recruiting
Music therapy for pain during surgery recovery
This trial studies whether listening to music can help reduce pain and improve recovery after common laparoscopic surgeries. It is for adults having gallbladder or appendix removal as same-day surgery.
Taichung, Not in USAAges 20–80 - NCT06471075Recruiting
Mindfulness for Pain Before Orthopedic Procedure
This study tests whether a short mindfulness (calm focus) exercise before an in-clinic orthopedic procedure can help reduce pain. If you are getting kyphoplasty or radiofrequency ablation at Tallahassee Orthopedic Center, this brief program might make your experience more comfortable.
Tallahassee, FloridaAges 18 years+ - NCT07524751Recruiting
Cultural Pain Management Program for Indigenous People
This study tests a pain management program designed specifically for American Indian and Alaska Native communities. If you have chronic pain (lasting over 3 months), this program teaches coping strategies that respect your culture and background.
Yakima, WashingtonAges 18 years+ - NCT07642674Recruiting
IV Pain Relief After Shoulder Arthroscopy Surgery
This study tests whether an intravenous pain medication (dexketoprofen) given during shoulder arthroscopy can reduce pain that returns after surgery ends. Researchers want to see if this approach helps keep patients more comfortable and need fewer pain medications overall.
Eskişehir, OdunpazarıAges 18–70 - NCT06574269RecruitingPhase 2
Study on TLC590 for pain after surgery
This trial tests a new pain medicine, TLC590, for people having one of several common surgeries, like bunion removal, hernia repair, breast augmentation, knee replacement, or tummy tuck. The goal is to see if it helps manage pain after the procedure.
Bellaire, TexasAges 18–70 - NCT06279650Recruiting
Self-hypnosis for chronic pain: follow-up interviews
This study asks people who took a self-hypnosis course for chronic pain about their experience. They will share their thoughts in an interview to help improve the program.
Montreal, QuebecAges 18 years+ - NCT06387290RecruitingPhase 3
Mindfulness and pain management for chronic pain on opioids
This study tests whether adding mindfulness training to standard pain management visits can help people with chronic pain who are taking long-term opioids. It aims to improve pain relief and reduce opioid-related risks.
La Jolla, CaliforniaAges 18 years+ - NCT06029075Recruiting
Brain stimulation for nerve pain after spinal injury
This study tests whether a gentle electrical current applied to the scalp can help relieve nerve pain that continues after an injury to the spinal cord, arm or leg amputation, or brain injury. Participants will continue their usual pain medications during the trial.
Houston, TexasAges 18–75 - NCT06495528Recruiting
Virtual reality for pain during port-a-cath placement
This study tests whether a virtual reality program (called Bliss) can help reduce pain and anxiety while you get a port-a-cath placed. It is for people who are having this small device put in for the first time as part of their cancer care.
AngersAges 18 years+ - NCT07198412Recruiting
Study on sedation's effect on back pain after spinal anesthesia
This study looks at whether giving sedation (medicine to help you relax) during spinal anesthesia can reduce back pain after surgery. It's for people having certain types of surgery on their lower abdomen or legs.
Banhā, Qalyubia GovernorateAges 18–65 - NCT07472296Recruiting
Comparing nerve blocks for heart surgery pain relief
This trial compares different types of nerve blocks to see which works best for managing pain after heart surgery through the breastbone. It may help reduce the need for strong pain medications.
Bursa, NilüferAges 18–80 - NCT06981312Recruiting
Internet therapy for teens with chronic pain
This study tests two online treatments for teenagers with chronic pain: Acceptance and Commitment Therapy (ACT) and pain education. It aims to see if these programs help reduce pain and improve daily life, and parents join a separate support program.
VallentunaAges 13–19 - NCT07194239Recruiting
Lifestyle medicine for chronic pain in older adults
This trial tests if lifestyle changes like diet and exercise can reduce chronic muscle or joint pain in older adults. It focuses on people with long-lasting pain from conditions like arthritis.
Hong KongAges 60 years+
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Pain Management trials by city
Studies with a site in or near these metro areas.
Pain Management trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for pain management?
- Yes. Clin2 currently lists 347 recruiting pain management studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain management trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain management trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.