Clin2
NCT07407504Possibly a fitRecruiting

Targeted therapy for cancers with a specific gene change

Locally Advanced or Metastatic Solid Tumors With PIK3CA-mutated

Part of Cancer clinical trials.

This trial tests an experimental drug called GenSci145, which may target cancers with a specific gene change called PIK3CA. The drug is given alone or with other treatments. The goal is to see if it can shrink tumors or slow cancer growth.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
186 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old.
  • Your tumor has a specific change called a PIK3CA mutation.
  • Your cancer has not responded to standard treatments or no standard treatment is available.
  • You have at least one tumor that can be measured on scans.
  • You are generally healthy enough to carry out everyday activities (ECOG score 0 or 1).
  • Your blood counts, liver, kidney, and blood sugar levels are within acceptable ranges.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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