Study of ABBV-438 for multiple myeloma patients
Part of Blood & lymphatic, Cancer, Heart & circulation, Immune system & allergy clinical trials.
This trial tests a new intravenous treatment, ABBV-438, for adults with multiple myeloma that has returned or not responded to prior therapies. It aims to see if the drug is safe, tolerable, and how it moves through the body.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have multiple myeloma that is relapsed (came back) or refractory (didn't respond) after your last treatment.
- You have at least one measurable sign of the disease, such as a certain level of M-protein in blood (≥0.5 g/dL) or urine (≥200 mg/24h), or abnormal free light chains in blood.
- You have tried 3 or more different treatment regimens, including a proteasome inhibitor, an immunomodulatory drug (like lenalidomide or pomalidomide), and an anti-CD38 therapy (like daratumumab), and you cannot tolerate or access other standard treatments.
- You do not have multiple myeloma that has spread to your brain or spinal cord.
- You have no history of certain lung conditions like idiopathic pulmonary fibrosis or organizing pneumonia.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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