Chemotherapy before surgery for advanced colon cancer with high CEA
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial compares giving chemotherapy before surgery versus going straight to surgery for people with locally advanced colon cancer and a high CEA blood marker. It aims to see if the chemo-first approach improves outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old.
- You have been diagnosed with colon cancer that has not spread to distant organs (stage II high-risk or stage III).
- Your blood test shows a CEA level above 5 before any treatment.
- You are healthy enough for daily activities (ECOG 0-1).
- You are willing to provide tumor and blood samples for genetic testing.
- You have not had another cancer and do not have certain serious health conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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