Chemo before surgery for colon cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests whether giving chemotherapy before surgery can improve outcomes for people with colon cancer that has grown into nearby tissue or lymph nodes but hasn't spread to other organs. It is for patients whose tumors are mismatch repair proficient (pMMR) or microsatellite stable (MSS).
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have colon or upper rectal cancer that has been confirmed by biopsy.
- Your tumor is mismatch repair proficient (pMMR) or microsatellite stable (MSS).
- You are scheduled for surgery with the goal of removing all cancer.
- Your cancer has grown into nearby tissue or lymph nodes (T3/T4 or N+) on CT or MRI scans.
- You have no evidence of cancer spread to other organs.
- You are in generally good health (ECOG score 0-2) and your blood counts and organ function are adequate.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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