Clin2
NCT07413549Worth exploringRecruiting

Stem cell injection for hepatitis B cirrhosis

Decompensated Hepatitis B Cirrhosis

Treatments studied

Part of Digestive system, Infections clinical trials.

This trial tests an injection of stem cells from donated umbilical cords to see if it can help people with advanced liver scarring from hepatitis B. You may be able to join if standard treatments haven’t helped enough and you aren’t able to get a liver transplant.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
76 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old.
  • You have been diagnosed with advanced liver scarring (cirrhosis) caused by hepatitis B that has led to complications like fluid buildup or bleeding.
  • You’ve had at least 3 months of standard medical treatments (including antivirals and supportive care) without enough improvement.
  • Your hepatitis B virus level is very low (under 2,000 IU per mL).
  • You are not a candidate for a liver transplant or don’t have a donor available.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05948982Not yet recruiting· Phase 1/Phase 2
Umbilical cord stem cells for advanced hepatitis B cirrhosis

This study tests whether stem cells from umbilical cord blood can safely help people with advanced liver scarring (cirrhosis) caused by hepatitis B. It may offer a new option for those who haven't improved with usual treatments.

NCT04357600Enrolling by invitation· Phase 1/Phase 2
Stem cell treatment for hepatitis B–related cirrhosis

This early-stage trial tests umbilical cord “mesenchymal” stem cells in people with liver scarring (cirrhosis) that is caused by hepatitis B. It may help improve liver function and related complications, but it is mainly designed to check safety and how well the treatment works.

Jakarta, DKI Jakarta
NCT03826433Recruiting· Phase 1
Study stem cell treatment for worsening hepatitis B cirrhosis

This Phase 1 study tests a stem cell product to see if it is safe and how it affects people with worsening hepatitis B-related cirrhosis. It may help researchers understand whether the treatment could improve liver function in this stage of illness.

Changsha, Hunan
NCT06884904Not yet recruiting· Phase 2/Phase 3
Stem cell infusion for liver failure from hepatitis B

This trial tests whether a stem cell infusion made from umbilical cord tissue can help people with severe liver failure caused by hepatitis B. The stem cells may reduce liver damage and improve recovery.

NCT05224960Recruiting· Phase 2
Stem cell treatment for worsening liver cirrhosis

This trial tests umbilical-cord stem cells to see if they can improve outcomes in people with decompensated (worsening) cirrhosis. You may be considered if your liver disease is moderate to severe (MELD 15–30) and you do not have certain high-risk problems right now.

Lanzhou, Gansu
NCT07472270Not yet recruiting· Phase 1
Stem cell therapy for liver cirrhosis

This study tests a new treatment using stem cells for people with liver cirrhosis caused by alcohol, hepatitis B, or hepatitis C. The goal is to see if it is safe and if it can help improve liver function.

Hanoi

Hear when a new Decompensated Hepatitis B Cirrhosis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.