Trust and the brain in Down syndrome and Fragile X
Part of Brain & nervous system, Genetic & congenital, Mental health clinical trials.
This study explores how people with Down syndrome or Fragile X syndrome learn to trust others. It uses simple tasks and a brain scan (MRI) to compare their responses with those of typically developing children and young adults.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have Down syndrome (with a confirmed extra chromosome 21) or Fragile X syndrome (confirmed by a specific genetic test), or be a typically developing volunteer.
- Your age must be between 13 and 29 (for Down syndrome, Fragile X, or age-matched controls) or between 3 and 9 (for mental age-matched controls).
- French must be your native language.
- You (or your legal guardian) must have French health insurance (social security).
- You must not have any metal implants, pacemaker, or other reasons that make an MRI unsafe (like severe claustrophobia).
- You cannot take part if you have certain medical conditions like uncontrolled epilepsy, significant hearing or vision problems, or a history of serious head injury (for typically developing controls).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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