Smart ankle brace and medicine to help kids with cerebral palsy walk better
Treatments studied
Part of Brain & nervous system clinical trials.
This trial tests whether a smart ankle brace combined with a medicine called 5-azacitidine can improve walking ability in children with cerebral palsy. The study compares the medicine to a placebo to see if it helps enhance mobility.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 8 and 17 years old with cerebral palsy and can walk (with or without help).
- You have a caregiver who can support you during training and study visits.
- Your height, weight, and BMI are within a typical range for children with cerebral palsy.
- You can walk for at least 6 minutes (using a walker or other help if needed).
- You have not had leg surgery in the last 12 months or botox injections in the last 3 months.
- You do not have certain health conditions like a weak immune system or severe osteoporosis.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if combining spinal cord stimulation with a drug called 5-azacitidine can improve movement and muscle control in children with cerebral palsy. It aims to help with daily activities like walking or using hands.
This study compares two types of ankle-foot braces to see which one helps children with cerebral palsy move better, join in activities, and wear the brace more consistently. It aims to find the best option for improving walking and daily life.
This trial tests a drug called 5-Azacytidine, which is being used in a new way—to help loosen tight muscles (contractures) in children with cerebral palsy. It aims to see if it can reduce the need for surgery.
This early (Phase 1) study tests a way to improve how well the ankle muscles help you push off when walking in cerebral palsy. If the ankle function improves, it may lead to a more comfortable and safer walking pattern.
This trial tests if robot-assisted training helps improve motor skills in children with cerebral palsy who can walk without major aids. It compares them to children without brain injuries.
This study tests whether starting movement exercises early after ankle surgery helps children with spastic cerebral palsy walk better and recover faster. The surgery corrects a tight ankle muscle (equinus deformity), and the trial compares early rehabilitation to standard care.
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