Testing an old drug for tight muscles in kids with cerebral palsy
Treatments studied
Part of Bones, joints & muscles, Brain & nervous system clinical trials.
This trial tests a drug called 5-Azacytidine, which is being used in a new way—to help loosen tight muscles (contractures) in children with cerebral palsy. It aims to see if it can reduce the need for surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child must have a diagnosis of cerebral palsy.
- They need to have tightness in their heel cord or hamstring that requires surgery.
- Your child should be between 2 and 18 years old.
- Their kidney and liver function must be normal, as shown by standard blood tests.
- For girls who have started their period, they must have a negative pregnancy test and use reliable birth control during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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