Clin2
NCT07439510Possibly a fitNot yet recruiting

Testing SPG601 for Fragile X syndrome in adult men

Fragile X Syndrome (FXS)

Part of Brain & nervous system, Genetic & congenital clinical trials.

This trial tests an experimental medicine called SPG601 to see if it can help with Fragile X syndrome symptoms in adult males. It also checks how safe the medicine is.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2/Phase 3
Enrollment
248 people
Ages
18 years to 45 years
Study type
Interventional

Who can take part

  • You must be a male between 18 and 45 years old.
  • You must have a confirmed diagnosis of Fragile X syndrome from genetic testing.
  • You must have a caregiver who can support you.
  • You should be generally healthy with no major medical problems.
  • You cannot have had seizures in the past 6 months or a history of epilepsy.
  • You cannot have a history of suicidal thoughts or substance abuse in the last 6 months.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07654114Recruiting· Phase 2
Testing CTH120 for men with Fragile X syndrome

This trial tests a new medicine called CTH120 to see if it is safe and helpful for adult men with Fragile X syndrome. You may be able to join if you meet certain health and age requirements.

Barcelona, Barcelona
NCT06868979Recruiting
Eye imaging for X-linked disorders

This study uses special eye imaging to look at changes in the brain and eyes of people with creatine transporter deficiency (a condition that affects brain energy) or fragile X syndrome. It aims to find a way to see these brain changes without needing a biopsy or spinal tap.

Bron
NCT06677866Recruiting
Group therapy for teens with Fragile X or autism

This trial tests if group cognitive behavioral therapy (CBT) can help teens with Fragile X syndrome or autism spectrum disorder improve social and emotional skills. It looks at how teens with these conditions respond to a structured group program.

Rome
NCT07434037Recruiting
Trust and the brain in Down syndrome and Fragile X

This study explores how people with Down syndrome or Fragile X syndrome learn to trust others. It uses simple tasks and a brain scan (MRI) to compare their responses with those of typically developing children and young adults.

Bron
NCT07328529Not yet recruiting· Phase 2
Testing a medication to reduce aggression in Fragile X

This trial is for men with Fragile X syndrome who have moderate to severe aggressive behavior. The study tests a new medication to see if it can help reduce aggression. You must have a caregiver who can help report your symptoms.

Sacramento, California
NCT07209462Recruiting· Phase 2
MRM-3379 for Fragile X Syndrome in males

This trial tests an investigational medicine called MRM-3379 in males with Fragile X syndrome. It looks at how the medicine affects thinking and behavior over time.

Phoenix, Arizona

Hear when a new Fragile X Syndrome (FXS) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.