PVX4 vaccine for HPV16-related cervical dysplasia
Part of Cancer, Women’s health & pregnancy clinical trials.
This trial tests a new vaccine called PVX4 for women with HPV16-related cervical dysplasia. It aims to see if the vaccine can help clear the high-risk HPV infection and the abnormal cells on the cervix.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman between 18 and 60 years old.
- You have been diagnosed with moderate or severe cervical dysplasia (CIN2 or CIN3) that is confirmed by a doctor.
- You test positive for HPV type 16 (a specific high-risk strain of HPV).
- You are HIV negative.
- You are willing to use birth control for 6 months after the study (if you could become pregnant).
- You have not had a cone biopsy, LEEP, or hysterectomy for cervical lesions before.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This early-phase study tests a vaccine designed to help your immune system fight HPV16, a type of human papillomavirus linked to abnormal cells in the cervix. You may or may not be living with HIV, and the team will check safety and immune response after giving the vaccine in a specific way.
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