HPV cancer trial using immune T cells made for you
Treatments studied
Part of Cancer, Digestive system, Ear, nose & throat, Kidney & urinary, Mouth & dental, Women’s health & pregnancy clinical trials.
This Phase 1/2 trial tests a one-time infusion of special immune T cells made to recognize your HPV16 tumor. It may help your body attack the cancer, while researchers closely monitor safety and early effectiveness.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed cancer (carcinoma) that is locally advanced and HPV-related.
- Your tumor must test positive for HPV16 using a certified lab.
- You must have the matching genetics for the treatment: HLA-A*02:01 (often screened as “HLA-A*02,” then confirmed as A*02:01).
- You must have measurable cancer on scans/tests, and be age 18 or older.
- You must have enough healthy blood counts and organ function based on lab tests (blood, liver, kidneys, and clotting).
- You must be able and willing to sign consent and join long-term follow-up and blood/tissue sample study protocols.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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