Study of an experimental drug for high-grade brain tumors
Part of Cancer clinical trials.
This trial tests a new experimental drug (FZ-AD005) for people with a fast-growing brain tumor called high-grade glioma. The drug is designed to target and attack cancer cells that have a specific protein (DLL3) on their surface, which may help stop the tumor from growing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 70 years old.
- You have a type of brain cancer called high-grade glioma that has either just finished radiation or has come back after treatment.
- You must be able to give a sample of your tumor for testing, and the test must show a certain protein (called DLL3) is present.
- You should be able to take care of yourself and be up and about at least 70% of the time (Karnofsky score of 70 or higher).
- If you take steroids for brain swelling, the dose must be stable or decreasing for at least a week before the study starts.
- Your heart, lungs, liver, kidneys, and blood counts need to be in decent shape.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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