Repeat cryospray treatment for chronic bronchitis in COPD
Part of Infections, Lungs & breathing clinical trials.
This study tests a second round of a treatment called metered cryospray, which uses extreme cold to reduce the extra mucus and inflammation in the airways of people with chronic bronchitis. It is for people who have already completed two treatments in a previous cryospray study and may help improve breathing and quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have completed a previous metered cryospray study, including both treatment sessions.
- You must be under 80 years old.
- You must have had COPD with chronic bronchitis for at least 2 years, meaning a daily cough with mucus for 3 months in each of 2 consecutive years.
- Your lung function must be moderate to severe (GOLD 2 or 3), as measured by breathing tests.
- You must have been taking standard COPD medications for at least 3 months before joining.
- You must not smoke (including vaping or e-cigarettes) for at least 2 months before the study and agree to stay smoke-free during the study.
- You must be able to have two bronchoscopies (a procedure where a thin tube is inserted into your airways) and pause any blood-thinning medications if needed.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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