Empagliflozin added to usual care for bipolar depression
Treatments studied
Part of Hormones & metabolism, Mental health clinical trials.
This study tests whether adding empagliflozin, a medication that helps control blood sugar, to your current bipolar depression treatment can improve depressive symptoms. It may help if you have insulin resistance, a condition where your body doesn't use insulin well.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 65 years old.
- You have been diagnosed with bipolar disorder type I or II.
- You are currently experiencing a depressive episode, with a score of at least 15 on a standard depression scale.
- You are on a stable treatment for bipolar disorder, with no changes in the last 4 weeks.
- You have insulin resistance, shown by a HOMA-IR score of 1.8 or higher.
- You do not have diabetes, kidney disease, or other excluded conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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