Personalized linezolid dosing for drug-resistant TB treatment
Part of Brain & nervous system, Infections clinical trials.
This trial tests whether adjusting the dose of linezolid based on regular blood tests can help people with multidrug-resistant tuberculosis (MDR-TB) tolerate the medication better while on the BPaL or BPaL-M regimen. It aims to reduce side effects and improve treatment success.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with multidrug-resistant tuberculosis (MDR-TB).
- You are 15 years old or older.
- Your doctor has prescribed linezolid as part of the BPaL or BPaL-M treatment plan.
- You are not pregnant or breastfeeding.
- You do not have severe liver or kidney failure.
- You are not allergic to linezolid.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study checks if measuring the amount of linezolid medicine in your blood helps treat rifampin-resistant tuberculosis more safely and effectively. It is for people who have already started a treatment plan that includes linezolid.
This trial tests whether a personalized dosing approach for linezolid (an antibiotic) works better than the standard dose. It is for adults with pneumonia or skin/soft tissue infections who have just started or are about to start linezolid.
This trial tests a personalized treatment approach for people with rifampicin-resistant TB that is still sensitive to fluoroquinolones. It aims to find the best combination of medicines based on your specific TB profile.
This trial tests a three-drug combination (bedaquiline, delamanid, and linezolid) to see if it's safe and works well for people with multi-drug resistant or rifampicin-resistant tuberculosis. It may offer a new treatment option if standard drugs aren't working.
This study tests how best to adjust the dose of an antibiotic called linezolid for people on dialysis. It aims to safely treat infections by using regular blood tests to guide dosing.
This trial studies a specific drug combination (BPaLM) for adults with drug-resistant pulmonary (lung) tuberculosis. If you qualify, the goal is to see whether this treatment is effective and safe for your type of infection.
Hear when a new Therapeutic Drug Monitoring (TDM) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.