Clin2
NCT07477587Possibly a fitRecruiting

Comparing two myeloma treatments for new patients

Multiple Myeloma (MM)

Part of Blood & lymphatic, Cancer, Heart & circulation, Immune system & allergy clinical trials.

This trial tests a new drug combination (HLX15-SC) against an approved treatment (DARZALEX FASPRO) along with lenalidomide and dexamethasone for people newly diagnosed with multiple myeloma who cannot have a stem cell transplant.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
258 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • 18 years or older
  • Newly diagnosed with multiple myeloma and not eligible for a stem cell transplant
  • Good overall health (ECOG score 0 or 1)
  • Adequate blood counts and kidney/liver function
  • Willing to use effective birth control
  • No prior cancer treatment for myeloma except a short course of steroids
  • No serious heart, lung, or other medical conditions
  • No active hepatitis B, C, or HIV infection

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07811986Not yet recruiting· Phase 2
New drug combo for advanced multiple myeloma

This trial tests a new treatment combination for multiple myeloma that has returned or stopped responding to previous therapy and has spread outside the bone marrow. It aims to see if the combination can shrink these tumors and improve outcomes.

Tianjin
NCT07828522Not yet recruiting· Phase 2
Study of F182112 with isatuximab and lenalidomide for newly diagnosed multiple myeloma

This trial tests a new combination of three drugs (F182112, isatuximab, and lenalidomide) for people who have just been diagnosed with multiple myeloma and have had little or no prior treatment. The goal is to see if this combination is safe and effective in controlling the disease.

NCT06895512Not yet recruiting· Phase 3
New drug combined therapy for untreated multiple myeloma

This study compares a new drug (HLX15-IV) with a standard treatment (Darzalex) when both are combined with lenalidomide and dexamethasone, for people newly diagnosed with multiple myeloma who cannot have a stem cell transplant. The goal is to see which combination works better and is safe.

Shanghai, Shanghai Municipality
NCT07247097Not yet recruiting· Phase 2
Comparing two drug combinations for newly diagnosed multiple myeloma

This trial tests two different drug combinations for people newly diagnosed with multiple myeloma who are not getting a stem cell transplant right away. It compares one drug (elranatamab) to another (daratumumab), both given with a standard three-drug regimen called RVd Lite, to see which works better.

Boston, Massachusetts
NCT07285239Recruiting· Phase 3
Comparing two drug combinations for newly diagnosed multiple myeloma

This trial compares two different combinations of medications for people with newly diagnosed multiple myeloma who are not planning to have a stem cell transplant. It looks at whether adding a targeted antibody drug is as effective as the standard approach.

La Crosse, Wisconsin
NCT07095452Recruiting· Phase 2/Phase 3
Newly diagnosed myeloma: comparing drug combinations for non-transplant patients

This trial tests a new combination of two drugs (etentamig and daratumumab) against the current standard of daratumumab plus lenalidomide and dexamethasone in people recently diagnosed with multiple myeloma who cannot have a stem cell transplant. The goal is to see which combination better controls the disease while keeping side effects manageable.

Scottsdale, Arizona

Hear when a new Multiple Myeloma (MM) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.