Comparing two painkillers for nausea after brain surgery
Treatments studied
Part of Brain & nervous system, Cancer, Ear, nose & throat clinical trials.
This trial tests if a newer painkiller (oliceridine) causes less nausea after a specific type of brain surgery than the standard painkiller (sufentanil). If you are having CPA region surgery and will receive a patient-controlled pain pump, this study may help find a better option for managing pain with fewer side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are scheduled for elective CPA region surgery (a type of brain surgery near the hearing and balance nerve).
- You are between 18 and 65 years old.
- Your physical health is rated as ASA I, II, or III (generally healthy or with mild to moderate illness).
- You are willing and able to provide written consent to join the study.
- You have not taken strong painkillers (like morphine or oxycodone) for a week or more before the trial.
- You have no severe heart, lung, liver, kidney, or other major diseases, and you are not in the ICU on a breathing tube after surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares two pain medicines given after surgery to see which provides better pain relief with fewer side effects in people who have obstructive sleep apnea. It aims to improve safety and comfort for sleep apnea patients recovering from non-cardiac surgery.
This study tests whether a new pain medication (oliceridine) given through an IV patient-controlled pump can reduce chronic pain after lung surgery. Participants will receive either oliceridine or a standard opioid for pain control after a minimally invasive lung resection. The study will follow patients for several months to see if they develop long-term pain.
This trial tests a combination of two pain-management approaches—a long-acting numbing medicine injected near nerves and a self-administered opioid—to see if they help your gut function better and control pain after bowel or colon surgery.
This trial tests whether avoiding opioid painkillers during anesthesia for brain tumor removal can be safe and effective. It may help patients recover with fewer side effects.
This trial tests a new pain medicine (Tegileridine) against a standard one (Sufentanil) during laparoscopic surgery. It is for patients who have a high risk of nausea and vomiting after surgery.
This trial tests a pain-relief medication called oliceridine for patients recovering from brain tumor removal surgery. The study looks at how well it helps manage pain and any side effects on digestion during recovery.
Hear when a new PONV trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.