Comparing two painkillers for nausea after brain surgery
Treatments studied
Part of Brain & nervous system, Cancer, Ear, nose & throat clinical trials.
This trial tests if a newer painkiller (oliceridine) causes less nausea after a specific type of brain surgery than the standard painkiller (sufentanil). If you are having CPA region surgery and will receive a patient-controlled pain pump, this study may help find a better option for managing pain with fewer side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are scheduled for elective CPA region surgery (a type of brain surgery near the hearing and balance nerve).
- You are between 18 and 65 years old.
- Your physical health is rated as ASA I, II, or III (generally healthy or with mild to moderate illness).
- You are willing and able to provide written consent to join the study.
- You have not taken strong painkillers (like morphine or oxycodone) for a week or more before the trial.
- You have no severe heart, lung, liver, kidney, or other major diseases, and you are not in the ICU on a breathing tube after surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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