Study of two diabetes drugs for weight and blood pressure
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests two medications (semaglutide and tirzepatide) to see how they affect blood pressure and heart function in people with different body weights and blood pressures. You would receive one of the drugs and have your heart and blood pressure monitored.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 50 years old.
- You are a nonsmoker.
- You fall into one of these groups: normal weight (BMI 18.5-24.9) with normal blood pressure, or obese (BMI 30 or higher) with either normal blood pressure or mild high blood pressure.
- You are not taking any heart or blood pressure medications regularly (for the normal-weight group) or can skip your blood pressure pills on study mornings (for the high-blood-pressure group).
- You do not have diabetes, a pacemaker, heart disease, kidney problems, or certain other medical conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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