Testing zongertinib with chemo and immunotherapy for advanced lung cancer
Treatments studied
Part of Cancer, Lungs & breathing clinical trials.
This trial tests a new drug called zongertinib combined with chemotherapy, with or without pembrolizumab (an immunotherapy), for people with advanced non-small cell lung cancer that has a specific change in the HER2 gene. The goal is to see how safe and well-tolerated the combination is.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older
- You have advanced or spreading non-squamous non-small cell lung cancer with a HER2 mutation
- You have not had any prior treatment for your advanced cancer
- You have at least one tumor outside the brain that can be measured
- You are able to have platinum-based chemotherapy and pembrolizumab, if given
- Your daily activity level is good (ECOG score 0 or 1)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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