Upadacitinib for erosive lichen planus and lichen planopilaris
Treatments studied
Part of Skin clinical trials.
This trial tests a pill called upadacitinib to see if it can reduce painful mouth sores and scalp hair loss caused by lichen planus. It may help people who have not gotten better with topical steroid creams.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 64 years old.
- You have a confirmed diagnosis of lichen planus in the mouth or on the scalp (biopsy-proven).
- Your lichen planus is moderate or severe and has not improved enough with strong steroid creams.
- You do not have active infections like tuberculosis, HIV, or hepatitis B or C.
- You have not had a recent heart attack, stroke, or blood clot, and you do not have a history of cancer (except treated skin cancer).
- If you are able to become pregnant, you must have a negative pregnancy test and agree to use effective birth control during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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