Upadacitinib for erosive mouth and scalp lichen planus
Treatments studied
Part of Skin clinical trials.
This trial tests a pill called upadacitinib (a JAK inhibitor) for people with erosive lichen planus affecting the mouth or scalp. It aims to see if the drug can reduce inflammation and improve symptoms when topical steroids aren't enough.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 64 years old.
- You have a type of lichen planus that affects the mouth or scalp, confirmed by a biopsy.
- Your lichen planus is moderate to severe, and strong steroid creams haven't helped enough.
- You are not pregnant or breastfeeding, and agree to use effective birth control if needed.
- You do not have certain serious infections, a history of shingles or herpes, or an organ transplant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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