A new drug plus letrozole for advanced HR+ breast cancer
Treatments studied
Part of Cancer clinical trials.
This trial tests a new medicine (BGB-43395) combined with letrozole against the usual CDK4/6 inhibitor plus letrozole. It is for people with advanced or metastatic HR-positive, HER2-negative breast cancer who have not yet had treatment for advanced disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- Your breast cancer is HR-positive and HER2-negative and has spread to other parts of the body or is locally advanced.
- You have not had any treatment for advanced or metastatic breast cancer before.
- You are in generally good health (able to do daily activities with little or no help).
- You do not have untreated or uncontrolled brain metastases or leptomeningeal disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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