Ultrasound test for diagnosing a rare liver blood vessel disorder
Part of Digestive system clinical trials.
This study uses a special ultrasound with contrast to help tell apart two conditions that cause high blood pressure in the liver: porto-sinusoidal vascular disorder (a rare disease of the liver's small blood vessels) and cirrhosis (scarring of the liver). The test may help avoid the need for a liver biopsy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be at least 18 years old.
- You must have been diagnosed with either porto-sinusoidal vascular disorder (confirmed by liver biopsy) or cirrhosis (confirmed by biopsy or other tests).
- You must have signs of high blood pressure in the liver, such as enlarged veins in the stomach or esophagus, or a history of bleeding from these veins.
- You must be able to understand the study and give written consent.
- You must not have other causes of liver problems, such as certain blood clots, heart failure, or other liver diseases.
- You must not have had liver or spleen surgery, or have a TIPS (a tube placed in the liver to reduce pressure).
- You must not be allergic to the contrast agent used (SonoVue) or have certain heart or lung conditions.
- You must not be pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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