Clin2
NCT07494435Possibly a fitNot yet recruiting

WGI-0301 with nivolumab for advanced liver or kidney cancer

Hepato Cellular Carcinoma (HCC)Renal Cell Cancer

Treatments studied

Part of Cancer, Kidney & urinary, Women’s health & pregnancy clinical trials.

This study tests an experimental drug (WGI-0301) combined with an FDA-approved immunotherapy drug (nivolumab, also known as Opdivo) for advanced liver or kidney cancer. The goal is to see if this combination is safe and effective for patients whose cancer has either not responded to standard treatment or has not been treated yet.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
230 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old.
  • You have either advanced liver cancer (HCC) that has progressed after first-line treatment, or advanced kidney cancer (RCC) that has not been treated or has progressed after first-line therapy.
  • Your liver function is adequate (Child-Pugh Class A or B score ≤7).
  • You are able to perform daily activities with some help (ECOG score 0 or 1).
  • You must have at least one measurable tumor that has not been treated with local therapy, or a new area of progression.
  • You must have adequate blood counts and organ function, and you cannot have major bleeding risks or severe autoimmune disease.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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