Venlafaxine for rheumatoid arthritis pain and mood
Part of Bones, joints & muscles, Immune system & allergy, Skin clinical trials.
This trial tests if adding venlafaxine, a medication often used for depression and anxiety, can help reduce rheumatoid arthritis symptoms in people who still have moderate to high disease activity despite standard treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older and have rheumatoid arthritis.
- You have been on stable disease-modifying drugs (with or without steroids) for at least 6 months.
- Your arthritis is still moderately or very active despite these treatments.
- You are not taking biologic drugs or targeted DMARDs.
- You are not pregnant or breastfeeding, and not using MAOIs or other antidepressants.
- You have no uncontrolled high blood pressure, unstable heart conditions, or serious bleeding risk.
- You have no history of psychosis, mania, current suicidal thoughts, or substance abuse.
- Your kidney and liver function are within safe limits.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether eye-movement therapy (EMDR) can reduce long-lasting pain in people with rheumatoid arthritis (RA). You may be eligible if your RA has been relatively stable, your pain is still high, and you can take part in therapy sessions safely.
This Phase 1/2 study tests whether fexofenadine (an allergy medicine) can improve symptoms and inflammation in people with active rheumatoid arthritis. Participants may be assigned to different treatment groups, and the study looks at safety and early signs of benefit.
This study tests whether desloratadine, an allergy medication, can help reduce rheumatoid arthritis symptoms when added to your current treatments. Researchers want to see if it reduces joint swelling and pain alongside your existing therapy.
This study tests whether adding roflumilast, a new medication, to your current rheumatoid arthritis treatment can help reduce joint inflammation and improve your symptoms. You would take it alongside methotrexate, a common RA medication you may already be using.
This study tests whether two drugs—roflumilast and desloratadine—added to your current rheumatoid arthritis medications can reduce joint inflammation and pain. You'd take these as add-ons to your existing treatment to see if they help control your disease better.
This trial tests whether venlafaxine, a medication usually used for mood, can help reduce chronic low back pain in people who do not have depression or other serious health issues. If you have had moderate to severe back pain for over 3 months with no known cause, you may be able to join.
Hear when a new Rheumatoid arthritis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.