Testing disulfiram for rheumatoid arthritis with extra weight
Treatments studied
Part of Bones, joints & muscles, Hormones & metabolism, Immune system & allergy, Skin clinical trials.
This study tests whether disulfiram (a drug used for alcohol dependence) can help reduce inflammation and joint pain in people with rheumatoid arthritis who are overweight. You'll continue your usual arthritis treatment, and the study will check if adding this drug improves your symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have been diagnosed with rheumatoid arthritis by a doctor.
- Your arthritis is active — meaning you have joint pain, swelling, or stiffness despite your current treatment.
- You have been on a stable dose of your arthritis medication (such as methotrexate or hydroxychloroquine) for at least 3 months.
- You are willing to completely avoid alcohol for the entire study.
- You do not have serious liver, kidney, or heart problems, and you are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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