Clin2
NCT07511894Possibly a fitNot yet recruiting

Beta-Blockers with Immunotherapy for Gastric Cancer

Gastric Cancer

Treatments studied

Part of Cancer, Digestive system clinical trials.

This study tests whether a blood-pressure medication called a beta-blocker helps immunotherapy work better for gastric (stomach) cancer patients before surgery. You would receive immunotherapy drugs first, then have surgery, while taking a beta-blocker for high blood pressure.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
33 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • Age 18–75 years
  • Diagnosed with gastric adenocarcinoma (stomach cancer) confirmed by biopsy
  • High blood pressure (systolic ≥140 or diastolic ≥90 mmHg) that your doctor wants to treat with a beta-blocker
  • Good overall health (ECOG score 0–1: able to do normal activities or mostly able)
  • Your doctor believes you need immunotherapy before surgery to remove your stomach cancer
  • No other serious medical conditions that would prevent safe use of beta-blockers

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07595523Not yet recruiting· Phase 2
Immunotherapy before surgery for advanced gastric cancer

This trial tests two immunotherapy drugs given before surgery for locally advanced gastric cancer that has a specific genetic marker (MSI-H or dMMR). The goal is to shrink the tumor and improve outcomes before removing it surgically.

NCT06915389Recruiting
Gastric cancer: predicting immune therapy side effects

This trial studies whether blood tests before treatment can predict side effects from immunotherapy (PD-1/PD-L1 inhibitors) in people with gastric cancer. If you are about to start this type of treatment, your participation could help doctors manage side effects better.

Xining, Qinghai
NCT07277439Recruiting· Phase 2
Immunotherapy and chemoradiation before surgery for stomach cancer

This study tests combining an immunotherapy drug (PD-1 inhibitor) and a medication to boost your immune system (thymalfasin) with standard chemotherapy and radiation before surgery for stage III cancer where the stomach meets the esophagus. The goal is to see if this approach can shrink the tumor and improve outcomes.

Nanjing, Jiangsu
NCT06759233Not yet recruiting· Phase 2
Cryoablation and immunotherapy for advanced gastric cancer

This trial uses a freezing technique (cryoablation) combined with an immunotherapy drug (PD-1 inhibitor) for people with advanced stomach cancer that has spread or cannot be removed by surgery. It's for those whose cancer has continued to grow after one or two types of chemotherapy.

Shanghai
NCT06980389Not yet recruiting· Phase 2
Radiation, chemo, and immunotherapy for advanced gastric cancer

This trial tests a combination of short-course radiation, standard chemotherapy, and an immunotherapy drug (a PD-1 inhibitor) for people with advanced or metastatic gastric cancer that hasn't spread to lymph nodes. The goal is to see if this approach can help shrink or control the tumor.

Guangzhou, Guangdong
NCT07353294Enrolling by invitation· Phase 1
Propranolol plus immunotherapy and chemo before bladder cancer surgery

This trial tests adding a blood pressure medication (propranolol) to a combination of immunotherapy (tislelizumab) and chemotherapy before surgery for bladder cancer that has spread to lymph nodes. It aims to see if this can help shrink the tumor before it is removed.

Guangzhou, Guangdong

Hear when a new Gastric Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.