Using dye imaging to diagnose bile duct blockage in infants
Treatments studied
Part of Digestive system, Genetic & congenital clinical trials.
This trial tests whether a special fluorescent dye called indocyanine green (ICG) can help doctors better diagnose biliary atresia—a rare condition where a baby's bile ducts don't form properly. The dye is used during an imaging scan to light up the bile system so doctors can see it more clearly.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your baby is less than 3 months old
- Your baby has cholestasis, meaning their liver isn't filtering bile properly (elevated direct bilirubin level)
- Your baby is already scheduled for a HIDA scan (a standard imaging test that looks at bile flow)
- Your baby's kidneys are working well (no kidney disease)
- Your baby has no severe bowel bleeding or history of bowel surgery
- Your baby has no allergies to iodine, shellfish, or the ICG dye itself
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests if a special dye (ICG) and a camera can help doctors see blocked bile ducts in newborns with jaundice, so they can diagnose biliary atresia faster and without extra procedures.
This study tests whether a simple stool card can help spot biliary atresia early in babies with jaundice. If your baby has high direct bilirubin levels, this trial may help catch the condition sooner.
This trial tests whether a special dye (ICG) seen during your surgery can help doctors better identify the edges of a tumor in bone or soft tissue. It may help ensure as much of the tumor is removed as safely as possible.
This trial tests if using a special green dye (ICG) during emergency gallbladder removal helps surgeons see the bile ducts better and reduce complications. It is for adults with acute cholecystitis who are having a planned laparoscopic (keyhole) surgery.
This trial studies whether a special IV dye (indocyanine green, or ICG) can help surgeons during an operation to fix a baby’s esophagus blockage with an abnormal connection to the windpipe. It may help improve how the repair is done, but eligibility depends on baby’s safety factors for using the dye.
This trial tests whether a special green dye helps surgeons see the bile duct more clearly during keyhole gallbladder removal. It may reduce the risk of injury.
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