Less invasive valve replacement for severe aortic stenosis
Part of Heart & circulation clinical trials.
This study tests whether a less invasive valve replacement (TAVI) can be done safely in hospitals that don't have a full heart surgery team on site. If you have severe aortic stenosis and are 70 or older, this trial might offer a new option with a shorter recovery than open-heart surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have severe narrowing of your aortic valve, based on an echo (ultrasound of the heart) showing a high pressure or small valve opening.
- You have symptoms from this valve problem, such as chest pain, shortness of breath, or fatigue when doing everyday things.
- You are 70 years old or older.
- You are a candidate for a procedure through a blood vessel in your leg (called transfemoral access).
- You have not had aortic valve surgery before, and your valve has three leaflets (not bicuspid).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This study tests a catheter-based procedure to replace a narrowed aortic valve without traditional open-heart surgery. It's designed for patients who are at higher risk for surgery due to age, health conditions, or anatomy.
This study tests whether TAVI (a procedure to replace your heart valve without open-heart surgery) can be done safely at centers that do not have on-site heart surgery backup. It looks at how well patients do after the procedure, focusing on safety and recovery.
This trial looks at placing a new aortic valve through the groin (transfemoral) without needing on-site heart surgery for people who are considered very high risk for standard open-heart valve surgery. It aims to measure early outcomes to see how safe and effective this approach is for frail or complex patients.
This trial compares a less invasive valve replacement (TAVR) with traditional open-heart surgery for people with a specific type of severe aortic valve narrowing (bicuspid valve). It aims to see which approach works better for those at intermediate or low surgical risk.
This study tests a new replacement valve for the aortic heart valve, delivered through a catheter (a thin tube) — a procedure called TAVR. It is for people who have severe aortic stenosis and are not good candidates for open-heart surgery.
This trial tests a new type of aortic valve replacement that can be inserted without open-heart surgery. It's designed for people with severe aortic stenosis who are not suitable for a standard operation.
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